Neferkitty was a High Priestess for the cat god Cat-Ra. She was very ambitious of power, since they once controlled humanity. Eventually humans rebelled against them and they were banished through a magical portal.
In the episode Garfield and Odie entered the portal where they were proclaim pharaohs of Egypt. After escaping with Garfield and Odie Neferkity, Liz's niece calls Neferkitty Fuzz button
Neferkitty bears some resemblances to Arlene, but their personalities are completely different.
Her name is a play on Nefertiti, the Great Royal Wife (that is, queen consort) to the pharaoh Ahkenaten.